Albany Internal Medicine
Smoking is the most common cause of COPD. Other things that may irritate the lungs and contribute to COPD include:
People with a family history of COPD are more likely to get the disease if they smoke.
Rarely, a genetic condition called alpha-1 antitrypsin deficiency may play a role in causing COPD.
Most people with COPD are at least 40 years old or around middle age when symptoms begin.