Physician (MD, DO)
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Joel Siegel, M.D.
120 North Ashwood Avenue
Ventura, California 93003 [MAP]
For an appointment, call (805) 658-5800
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Medical Expertise

Dr. Siegel specializes in the diagnosis and treatment of skin conditions, including acne, eczema, psoriasis and skin cancer.

Tips & Wisdom

5-FU Topical Tips with Dr. Siegel

5-Fluorouracil (5-FU) is a medication applied to the skin for the treatment of actinic keratoses.

5-FU is a topical chemotherapy that kills sun-damaged skin cells. It can also damage normal skin cells and result in significant skin irritation.

Using 5-FU usually results in a mild to a severe burning sensation. After 5-10 days of treatment, the sun-damaged parts of treated skin become red and irritated. Sores and crusts may appear with ongoing use. If you have severe sun-damage, you may have severe crusting -- YOUR SKIN MAY LOOK HORRIBLE!! Don't get alarmed - this reaction means that the medication is working. These raw areas result from the destruction of defective skin cells.  If you are not experiencing discomfort, tenderness, or itching, continue applying the medication. If you do have discomfort, discontinue the medication and make a note of the date you stopped it.


  • Wash the area to be treated with plain water.
  • Apply a small amount of the medication on the skin with your fingertip. It is important to apply the medication to the entire area, not just to the lesions which are visible to the naked eye.
  • After applying, wash hands.
  • Apply sunscreen with an SPF of 30 or higher. This medication will make you very sensitive to sunlight.

Conditions Treated

Aging Skin & Wrinkles
Allergic Contact Dermatitis
Atopic Dermatitis
Hair Loss (Balding)
Seborrheic Keratosis
Skin Cancer

About Me

Dr. Joel Siegel, MD is a board-certified dermatologist providing care to patients in Camarillo and Ventura, California at the Centers for Family Health, part of the Community Memorial Health System.

Education & Training

Dr. Joel Siegel received his medical degree from State University of New York and completed a dermatology residency at University Health Center of Pittsburgh.
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