Kalamazoo Nerve Center, PLLC

Levodopa and carbidopa (Duopa®)

Levodopa and Carbidopa

Levodopa (also called L-dopa) is main component of Parkinson's disease treatments. Nerve cells can use levodopa to make dopamine and replenish the brain's dwindling supply.

The addition of carbidopa to levodopa provides benefits over the use of levodopa alone.

The use of carbidopa delays the conversion of levodopa into dopamine until it reaches the brain, preventing or diminishing some of the side effects that often accompany levodopa therapy.

Carbidopa also reduces the amount of levodopa needed.

Reference: National Institute of Neurological Diseases and Stroke (NINDS)